4 0
Identification of four iridoids in the pharmacologically-active fraction of Vitex negundo by Fabian L. Dayrit and Lilita G. Lagurin 6 6 - - - - - - - - . - . - 0 . - . - 0 .
Reported in this paper is the isolation and identification of 4 iridoids from the pharmacologically active fraction of the leaves of V. negundo. Three of the iridoids contain glucosyl and parahydroxybenzoic acid moities. To date, only a limited number of studies were undertaken on the biological activity of iridoids although these are known to be active constituents in a number of traditional medicinal plants. Among the properties attributed to iridoids include analgesic and anti-inflammatory activities. The 4 iridoids isolated and identified are 2'-p-hydroxybenzoyl mussaenosidic acid, 6'-p-hydroxybenxoyl mussaenosidic acid, agnuside and lagundinin
5
5
2 = =
2
2 --0------
6 --0-- 2 --------
0 2 --
--20------
Pharmacology;Iridoids;Anti-inflammatory agents ------Tridoids;Agnuside;Vitex negundo--Lagundi;Analgesic--
--------20--
----2
/ 2
/ 2
/
/
Identification of four iridoids in the pharmacologically-active fraction of Vitex negundo by Fabian L. Dayrit and Lilita G. Lagurin 6 6 - - - - - - - - . - . - 0 . - . - 0 .
Reported in this paper is the isolation and identification of 4 iridoids from the pharmacologically active fraction of the leaves of V. negundo. Three of the iridoids contain glucosyl and parahydroxybenzoic acid moities. To date, only a limited number of studies were undertaken on the biological activity of iridoids although these are known to be active constituents in a number of traditional medicinal plants. Among the properties attributed to iridoids include analgesic and anti-inflammatory activities. The 4 iridoids isolated and identified are 2'-p-hydroxybenzoyl mussaenosidic acid, 6'-p-hydroxybenxoyl mussaenosidic acid, agnuside and lagundinin
5
5
2 = =
2
2 --0------
6 --0-- 2 --------
0 2 --
--20------
Pharmacology;Iridoids;Anti-inflammatory agents ------Tridoids;Agnuside;Vitex negundo--Lagundi;Analgesic--
--------20--
----2
/ 2
/ 2
/
/