Normal view MARC view ISBD view

Cytotoxicity study of selected ethnomedicinal plants used by Dumagats in Barangay San Lorenzo, Norzagaray and Kabayunan, Doña Remedios Trinidad, Bulacan Domingo, Mark Lloyd M., Gabales, Matthew, Guerra, Dominique Ann A., Lindo, Jacinta Sophia Reign M. 6

By: Domingo, Mark Lloyd M., Gabales, Matthew, Guerra, Dominique Ann A., Lindo, Jacinta Sophia Reign M. 4 0 16, [, ] | [, ] |

Contributor(s): 5 6 [] |

Language: Unknown language code Summary language: Unknown language code Original language: Unknown language code Series: ; 4544446Edition: Description: 148 pagesContent type: text Media type: unmediated Carrier type: volumeISBN: ISSN: 2Other title: 6 []Uniform titles: | | Related works: 1 40 6 []Subject(s): -- 2 -- 0 -- -- | -- 2 -- 0 -- 6 -- | 2 0 -- | -- -- 20 -- | | -- -- -- -- 20 -- | -- -- -- 20 -- --Genre/Form: -- 2 -- Additional physical formats: DDC classification: | LOC classification: | | 2Other classification:

Contents:

Action note: In: Summary: ABSTRACT: Many indigenous tribes do not have access to modern medicine, and for this reason they use ethnomedicinal plants, which are used to address several medical ailments. The risks to ethnomedicinal knowledge and practices in the Philippines, as well as the lack of information on traditional medicine, increase the risk of indigenous people being unaware of the potentially harmful and/or fatal cytotoxic activity of the plants. The present study was conducted to provide documentation of the ethnomedicinal knowledge and practice of Dumagats in Barangays San Lorenzo and San Mateo, Norzagaray, Bulacan. This study also determines the cytotoxicity of three selected common medicinal plants, Artemisia vulgaris, Blumea balsamifera, and Coleus amboinicus. The three were selected and subjected to crude ethanolic leaf extraction. Extracts were then investigated for cytotoxicity potential using brine shrimp lethality assay and trypan blue assay. A total of 22 ethnomedicinal plants were used to treat common ailments. The most commonly used plant parts are the leaves, and these ethnomedicinal plants were often decocted and taken orally. A. vulgaris, B. balsamifera, S. spontaneum, and D. philippinensis were the most used plants in the barangays, with a use value of 0.57. Exposure of S. cerevisiae S-04 strain to A. vulgaris, C. amboinicus, and B. balsamifera extracts at varying concentrations and durations revealed distinct cytotoxic effects. At higher concentrations, significant decreases in cell viability were observed over time, indicating concentration-dependent cytotoxicity. Conversely, lower concentrations exhibited minimal cytotoxic effects. Prolonged exposure exacerbated cytotoxicity, suggesting time-dependent effects. These findings highlight the concentration- and time-dependent cytotoxic effects of plant extracts on yeast cells. Overall, this research emphasizes the significance of documenting ethnomedicinal practices and assessing the cytotoxicity of medicinal plants, shedding light on their varying effects over time and concentration, crucial for understanding their potential impact on health. Other editions:

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings ( 1 )
Title notes
Comments ( 0 )

Item type	Current location	Home library	Collection	Call number	Status	Date due	Barcode	Item holds
Book	PLM	PLM Filipiniana Section	Filipiniana-Thesis	QH301 D66 2024 (Browse shelf)	Available		FT8437

Total holds: 0

Browsing PLM Shelves , Shelving location: Filipiniana Section , Collection code: Filipiniana-Thesis Close shelf browser

Previous	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	No cover image available	Next
Previous	QH301 C37 2023 Toxicity evaluation and anthelmintic potential of muntingia calabura L. (Aratiles) methanolic leaf extract	QH301 D36 2024 Air pollution tolerance index (APTI) and antioxidant potentials using DPPH assay of mature leaves from selected tree species llong Intramuros Walls, Manila	QH301 D56 2023 In vitro pediculicidal and ovicidal activity of tagetes patula methanolic leaf extract against pediculus humanus capitis (Human Head Lice)	QH301 D66 2024 Cytotoxicity study of selected ethnomedicinal plants used by Dumagats in Barangay San Lorenzo, Norzagaray and Kabayunan, Doña Remedios Trinidad, Bulacan	QH301 F45 2024 Antibacterial potential of lichen extracts and insights into their diversity in selected areas in Manila, Philippines	QH301 G37 2023 Prevalence and associated environmental risk factors of angiostrongylus cantonensis infection in pomacea canaliculata (Golden Apple Snail) in selected Barangays of San Juan, Batangas, Philippines	QH301 M37 2023 Abundance, characteristics, and potential neuromuscular effects of ingested microplastics In channa striata (Mudfish) and oreochromis niloticus (Nile Tilapia) from Napindan Channel of Pasig River, Taguig City	Next

Undergraduate Thesis: (Bachelor of Science in Biology) - Pamantasan ng Lungsod ng Maynila, 2024 56

ABSTRACT: Many indigenous tribes do not have access to modern medicine, and for this reason they use ethnomedicinal plants, which are used to address several medical ailments. The risks to ethnomedicinal knowledge and practices in the Philippines, as well as the lack of information on traditional medicine, increase the risk of indigenous people being unaware of the potentially harmful and/or fatal cytotoxic activity of the plants. The present study was conducted to provide documentation of the ethnomedicinal knowledge and practice of Dumagats in Barangays San Lorenzo and San Mateo, Norzagaray, Bulacan. This study also determines the cytotoxicity of three selected common medicinal plants, Artemisia vulgaris, Blumea balsamifera, and Coleus amboinicus. The three were selected and subjected to crude ethanolic leaf extraction. Extracts were then investigated for cytotoxicity potential using brine shrimp lethality assay and trypan blue assay. A total of 22 ethnomedicinal plants were used to treat common ailments. The most commonly used plant parts are the leaves, and these ethnomedicinal plants were often decocted and taken orally. A. vulgaris, B. balsamifera, S. spontaneum, and D. philippinensis were the most used plants in the barangays, with a use value of 0.57. Exposure of S. cerevisiae S-04 strain to A. vulgaris, C. amboinicus, and B. balsamifera extracts at varying concentrations and durations revealed distinct cytotoxic effects. At higher concentrations, significant decreases in cell viability were observed over time, indicating concentration-dependent cytotoxicity. Conversely, lower concentrations exhibited minimal cytotoxic effects. Prolonged exposure exacerbated cytotoxicity, suggesting time-dependent effects. These findings highlight the concentration- and time-dependent cytotoxic effects of plant extracts on yeast cells. Overall, this research emphasizes the significance of documenting ethnomedicinal practices and assessing the cytotoxicity of medicinal plants, shedding light on their varying effects over time and concentration, crucial for understanding their potential impact on health.

There are no comments for this item.

to post a comment.