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In-vitro anthelmintic potential of strongylodon macrobotrys (Tayabak) and dillenia philippinensis (Katmon) methanol leaf extract against caenorhabditis elegans 6

By: Jotham B. Naval Matthew Mark A. Martinez Janiz Alyna A. Ramos Frances Anne DR. Salazar Kim Colline Enriquez 4 0 16, [, ] | [, ] |

Contributor(s): 5 6 [] |

Language: Unknown language code Summary language: Unknown language code Original language: Unknown language code Series: ; 4507846Edition: Description: 92 pagesContent type: text Media type: unmediated Carrier type: volumeISBN: ISSN: 2Other title: 6 []Uniform titles: | | Related works: 1 40 6 []Subject(s): -- 2 -- 0 -- -- | -- 2 -- 0 -- 6 -- | 2 0 -- | -- -- 20 -- | | -- -- -- -- 20 -- | -- -- -- 20 -- --Genre/Form: -- 2 -- Additional physical formats: DDC classification: | LOC classification: | | 2Other classification:

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Action note: In: Summary: ABSTRACT: Infections caused by soil-transmitted helminths continue to be a common and prevalent health concern in the world. Herbal plants are utilized as alternatives to synthetic study anthelmintics since these drugs are sometimes subject to anthelmintic resistance. The was designed to examine the anthelmintic potential among the varying concentrations (0.2, 0.6, 0.8, 1.0, and 2.0 mg/mL) of Strongylodon macrobotrys and Dillenia philippinensis methanolic leaf extracts using Caenorhabditis elegans as the model species for soil-transmitted helminths. These concentrations were administered to the plates containing C. elegans to examine the mortality index and larval development of the free-living nematode. Results indicated that for 24 hours, both S. macrobotrys (95.83% mortality) and concentration, while for 48 hours best concentration of S. macrobotrys was 2.0 mg/mL ớ To a ong philippinensis (85.42% mortality) had 2.0 mg/mL as the best (100.00% mortality) while D. philippinensis' best concentration was 0.8 mg/mL 96.02% mortality) in terms of mortality. Larval development assay also reported anthelmintic properties with the lowest percentage being greater L4-adult stage percent compared to the M9 buffer (45.45% > 12.5%). Statistical analysis through ANOVA showed that there are no significant differences among the varying concentrations of both S. macrobotrys (0.23 > 0.05 at 24-hr and 48-hr) and D. philippinensis (0.73 > 0.05 at 24-hr; 0.63 > 0.05 at 48-hr), as well as between the most effective concentrations in 24-hr (0.71 > 0.05) and 48-hr (0.08 > 0.05) post-treatment. Other editions:

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Item type	Current location	Home library	Collection	Call number	Status	Date due	Barcode	Item holds
Book	PLM	PLM Filipiniana Section	Filipiniana-Thesis	QH301 N38 2023 (Browse shelf)	Available		FT8335

Total holds: 0

Undergraduate Thesis: (Bachelor of Science in Biology) - Pamantasan ng Lungsod ng Maynila, 2023 56

ABSTRACT: Infections caused by soil-transmitted helminths continue to be a common and prevalent health concern in the world. Herbal plants are utilized as alternatives to synthetic study anthelmintics since these drugs are sometimes subject to anthelmintic resistance. The was designed to examine the anthelmintic potential among the varying concentrations (0.2, 0.6, 0.8, 1.0, and 2.0 mg/mL) of Strongylodon macrobotrys and Dillenia philippinensis methanolic leaf extracts using Caenorhabditis elegans as the model species for soil-transmitted helminths. These concentrations were administered to the plates containing C. elegans to examine the mortality index and larval development of the free-living nematode. Results indicated that for 24 hours, both S. macrobotrys (95.83% mortality) and concentration, while for 48 hours best concentration of S. macrobotrys was 2.0 mg/mL ớ To a ong philippinensis (85.42% mortality) had 2.0 mg/mL as the best (100.00% mortality) while D. philippinensis' best concentration was 0.8 mg/mL 96.02% mortality) in terms of mortality. Larval development assay also reported anthelmintic properties with the lowest percentage being greater L4-adult stage percent compared to the M9 buffer (45.45% > 12.5%). Statistical analysis through ANOVA showed that there are no significant differences among the varying concentrations of both S. macrobotrys (0.23 > 0.05 at 24-hr and 48-hr) and D. philippinensis (0.73 > 0.05 at 24-hr; 0.63 > 0.05 at 48-hr), as well as between the most effective concentrations in 24-hr (0.71 > 0.05) and 48-hr (0.08 > 0.05) post-treatment.

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