Antibacterial Potential of pipinong-gubat (Melothria pendula) methanolic leaf and fruit crude extracts against staphylococcus aureus, escherichia coli, and bacillus cereus 6
By: Collamar, Jishra Loisa Cubacub, Precious Revilla, Daryl Christian Tayactac, Ted Emerson 4 0 16 [, ] | [, ] |
Contributor(s): 5 6 [] |
Language: Unknown language code Summary language: Unknown language code Original language: Unknown language code Series: ; 4507846Edition: Description: 136 pagesContent type: text Media type: unmediated Carrier type: volumeISBN: ISSN: 2Other title: 6 []Uniform titles: | | Subject(s): -- 2 -- 0 -- -- | -- 2 -- 0 -- 6 -- | 2 0 -- | -- -- 20 -- | | -- -- -- -- 20 -- | -- -- -- 20 -- --Genre/Form: -- 2 -- Additional physical formats: DDC classification: | LOC classification: | | 2Other classification:| Item type | Current location | Home library | Collection | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|---|---|
| Book | PLM | PLM Filipiniana Section | Filipiniana-Thesis | QK449 C65 2023 (Browse shelf) | Available | FT8314 |
Browsing PLM Shelves , Shelving location: Filipiniana Section , Collection code: Filipiniana-Thesis Close shelf browser
Undergraduate Thesis: (BS in Biology major in Medical Biology) - Pamantasan ng Lungsod ng Maynila, 2023 56
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ABSTRACT: Foodborne illnesses are among the growing list of infections that are becoming more difficult and even impossible to treat as antibiotics lose their effectiveness due to the increasing threat of antibiotic resistance emerging globally. The aim of this study was to examine the antibacterial potential of methanolic leaf and fruit crude extract of a noxious weed, Melothria pendula against some foodborne pathogens, Bacillus cereus, Escherichia coli and Staphylococcus aureus. Phytochemical analysis showed the presence of alkaloids, coumarins, flavonoids and terpenoids in both extracts. The mean zone of inhibition of the extracts showed that the concentration of methanolic leaf extract was efficacious at 10 mg/ml inhibiting B. cereus (1.27 ÷ 0.55) and E. coli (1.27 $ 0.55) and 5 mg/ml for S. aures (1.77 $ 0.57). The concentration of methanolic fruit extract was potent at 10 mg/ml for B. cereus (1.40 $ 0.40) and S. aureus (0.9 $ 0.61) and 20 mg/ml for E. coli (1.40 $ 0.40). The values were interpreted as resistant under the MIC guidelines of crude extract (Jamal, 2018) and ZOl guidelines for crude extract (Guevarra, 2005). Despite this interpretation, the extract still successfully inhibited growth in both MIC and ZOl, therefore, these findings support the traditional knowledge of localities in Tagalog areas and the study will serve as evidence of the antibacterial potential of Melothria pendula fruit and leaf extract. Considering the medical importance of the test microbial species, the results are promising for the development of new antimicrobial medicines. Keywords: Foodborne pathogens, phytochemical, antibiotic resistance
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