Busran, Haron C.; Broqueza, Einreb B.; Cardiņo Luis Gabriel L.; Legaspi, Sofia Jerica S.; Sorillo, Johana Catherine A.  4  0   <br/><br/>
Anthelmintic potentials of caralla brachiate (corkwood) and arenga tremula (dwarf sugar palm)        6 
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<br/><br/>   Undergraduate Thesis: (Bachelor of Science in Biology) - Pamantasan ng Lungsod ng Maynila, 2023 
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<br/><br/> ABSTRACt:  Parasitic helmnth infection remains a public health concern worldwide. Endemic plants with anthelmintic qualities can be a candidate for alternative resources. This study evaluates the anthelmic qualities can be a candidate for alternative resources. This study evaluates the anthelmintic potential of Carallia brachiate and Arenga tremula crude methanolic leaf extracts on Eudrilus eugeniae.  Qualitative phytochemical screening was conducted to determine the phytoconstituents of leaves. Both plants exhibited the presence of alkaloids, phenols, tannins, flavonoids, and steroids. Brine shrimp lethality assay was conducted for preliminary cytotoxic  activity and established working concentrations for adult worm motility assay. Median lethality concentration (LC50) in each plant was computed using probit analysis. The LC50 of Arenga tremula was 2.52 mg/ml while the Carallia brachiate was 2.36 uL/mL. The working concentrations for adult worm motility assay were: 0.59 uL/mL, 1.18 uL/mL, 177 uL/mL, 2.36uL/mL and 2.95uL/mL for C. brachiate; and 0.63 mg/mL, 1.26 mg/mL, 1.89 mg/mL, 2.52 mg/mL and 3.15 mg/mL for C. brachiate; and 0.63 mg/mL, 1.26 mg/mL, 1.89 mg/mL, 2.52 mg/mL and 3.15 mg/mL for A. tremula.  In motility assay, highest anthelminthic activity after 24 hours was observed in 2.52 mg/mL in Arenga tremula and 0.59 uL/mL in Carallia brachiate. Resultrs bfrom the Multivariate Analysis of Variance showed that time plays a significant role in the mortality of worms. Statistical results in varying concentrations show no significant differences in both plants. In comparison between the two plant species, mean mortality also showed no significant differences. Furthermore, results showed that both plants possess anthelmintic potential of the two plant extracts are not as effective compared to positive control albendazole.       
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