Bioactive Furanocoumarin Derivatives from Ficus pumila (Moraceae) 6
By: 4 0 16 [, ] | [, ] |
Contributor(s): Philippine Journal of Science 126 (2) : April - June 1997. pp. 143-153 5 6 [] |
Language: Unknown language code Summary language: Unknown language code Original language: Unknown language code Series: ; Manila : STII-DOST, 1997 46Edition: Description: Content type: text Media type: unmediated Carrier type: volumeISBN: ISSN: 2Other title: 6 []Uniform titles: | | Subject(s): -- 2 -- 0 -- -- | -- 2 -- 0 -- 6 -- | 2 0 -- | -- -- 20 -- | | -- -- Chemistry;Ficus Pumila -- Bioactive Furanocoumarin Derivatives;Antimocrobial -- Antimutagen -- | -- -- -- 20 -- --Genre/Form: -- 2 -- Additional physical formats: DDC classification: | LOC classification: | | 2Other classification:| Item type | Current location | Home library | Collection | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|---|---|
| Book | PLM | PLM Periodicals Section | Periodicals | Q75.P538 (Browse shelf) | Available | PER 1340C |
ABSTRACT The chloroform extract of Ficus pumila afforded bergapten and oxypeucedanin hydrate. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. The compounds were tested for antimicrobial activity against six microorganisms by the agar well method. Bergapten was found to inhibit the growth of Staphylococcus aureus, Eschericia coli and Salmonnella typhi, but was inactive against Trichophyton mentagrophytes, Mycobacterium pleie and Candida albicans. Oxypeucedanin hydrate inhibited the growth of Salmonella typhi, but was found inactive against the other five microorganisms. Both compounds were also tested for antimutagenic activity by the use of the micronucleus test. Results of the study polychromatic (MPCE) induced by mitomycin C by 44%, while oxypeucedanin hydrate reduced MPCE by 74%. 56
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