000			03701nam a2200289Ia 4500
001			90106
003			ft7766
005			20251117105828.0
008			240311n 000 0 eng d
040			_erda
041			_aengtag
050			_a QD190 E36 2023
082			_a.
100			_aIvan Lito Boy C. Echon; Reuben Miguel S. Felix; Gianny Piercee R. La Rosa; Kimberly Ann T. Mendoza and Sarah Grace S. Villanueva.
245		0	_aPhytochemical analysis, antioxidant assay, and cytotoxicity assay of ethanolic extracts of the aerial parts of five Philippine alocasia species
264			_a. _b. _cc2023
300			_bUndergraduate Thesis: (Bachelor of Science in Chemistry) - Pamantasan ng Lungsod ng Maynila, 2023.
336			_b. _atext _2rdacontent
337			_30 _b. _aunmediated _2rdamedia
338			_30 _b. _avolume _2rdacarrier
385			_a2
505			_aABSTRACT: Five Philippine Alocasia species (A. clypeolata, A. heterophylla, A. nycteris, and A. portei) were determined for the presence of phytochemicals, antioxidant, and cytotoxic activity to elucidate their pharmacological properties and lay the groundwork for further studies on their anticancer potential. The species under investigation were qualitatively tested for alkaloids, carbohydrates, cyanogenic glycosides, flavonoids, phenols, phytosterols, proteins, amino acids, saponins, tannins, and terpenes; most of which were determined to be present in the samples. Notable absences are saponins in A. clypeolata and A. portei, cyanogenic glycosides in A. heterophylla, and tannins in all species. All samples were determined to have strong antioxidant activity via DPPH free radical scavenging assay, and moderate to high cytotoxicity via brine shrimp lethality bioassay. In total phenolic content determination, the chosen methodology was incompatible with the quantitation of phenolic compunds in the sample, suggesting the use of higher extract concentrations in succeeding analyses. The presence of active metabolites in the extracts is inferred to be responsible for the positive results of the assays. The results suggest pharmacological potential and pursuance of future investigations on these Alocasia species for their anticancer capabilities.
520			_aABSTRACT: Five Philippine Alocasia species (A. clypeolata, A. heterophylla, A. nycteris, and A. portei) were determined for the presence of phytochemicals, antioxidant, and cytotoxic activity to elucidate their pharmacological properties and lay the groundwork for further studies on their anticancer potential. The species under investigation were qualitatively tested for alkaloids, carbohydrates, cyanogenic glycosides, flavonoids, phenols, phytosterols, proteins, amino acids, saponins, tannins, and terpenes; most of which were determined to be present in the samples. Notable absences are saponins in A. clypeolata and A. portei, cyanogenic glycosides in A. heterophylla, and tannins in all species. All samples were determined to have strong antioxidant activity via DPPH free radical scavenging assay, and moderate to high cytotoxicity via brine shrimp lethality bioassay. In total phenolic content determination, the chosen methodology was incompatible with the quantitation of phenolic compunds in the sample, suggesting the use of higher extract concentrations in succeeding analyses. The presence of active metabolites in the extracts is inferred to be responsible for the positive results of the assays. The results suggest pharmacological potential and pursuance of future investigations on these Alocasia species for their anticancer capabilities.
526			_aF
655			_aacademic writing
942			_alcc _cMS _01 _2lcc
999			_c24275 _d24275