000			04085nam a2200289Ia 4500
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003			ft7895
005			20251117103401.0
008			240722n 000 0 eng d
040			_erda
041			_aengtag
050			_aQD1 E83 2024
082			_a.
100			_aLian Adrielle T. Esconde, Ma. Angelica L. Ignacio, Amie Grace D. Jimenez, Jersey P. Marcelo, Angel Mikaela B. Villapando.
245		0	_aPhytochemical screening and in vitro analysis of hypoglycemic properties of selected cyrtochloa.
264			_a. _b. _cc2024
300			_bUndergraduate Thesis : (Bachelor of Science in Chemistry) - Pamantasan ng Lungsod ng Maynila, 2024.
336			_b. _atext _2rdacontent
337			_30 _b. _aunmediated _2rdamedia
338			_30 _b. _avolume _2rdacarrier
505			_aABSTRACT: The study investigated the phytochemical and hypoglycemic potential of Cyrtochloa fenixii, Cyrtochloa hirsute, Cyrtochloa luzonica, Cyrtochloa major, and Cyrtochloa toppingii, which are endemic to the Philippines, known by their common names Bolo, Baitu, Luzon bikal, Bikal baboy, and Bukawe, respectively. Through phytochemical screening and in vitro hypoglycemic analysis, the study addresses the need for natural remedies in managing diabetes mellitus. The analysis nof secondary metabolites revealed the presence of carbohydrates, flavonoids, phenols and saponins in all plant extracts, suggesting a potential impact on blood glucose control. Notably, presence of phytosterols were observed in all plants except Cyrtochloa luzonica, alkaloisa were found in all plants except Cyrtochloa hirsute and cyrtochloa luzonica, and all species lack glycosides and tannins. The species were ranked based on their concentrations of Total Flavonoid Content (TFC) and Total Phenolic Content (TPC), with Cyrtochloa toppingii having the highest concentration, followed by Cyrtochloa fenixii, Cyrtochloa luzonica, Cyrtochloa major. Among the five species studied, Cyrtochloa toppingii having the highest concentration of flavonoids and phenols showed the highest hypoglycemic activity. Correlation analyses revealed that TFC and TPC directly affect the alpha-amylase inhibition behaviors of plant extracts. In the hypoglycemic properties in terms of their effect on the glucose uptake of yeast cells, moderate and strong positive correlation to TPC and TFC were observed, respectively.
520			_aABSTRACT: The study investigated the phytochemical and hypoglycemic potential of Cyrtochloa fenixii, Cyrtochloa hirsute, Cyrtochloa luzonica, Cyrtochloa major, and Cyrtochloa toppingii, which are endemic to the Philippines, known by their common names Bolo, Baitu, Luzon bikal, Bikal baboy, and Bukawe, respectively. Through phytochemical screening and in vitro hypoglycemic analysis, the study addresses the need for natural remedies in managing diabetes mellitus. The analysis nof secondary metabolites revealed the presence of carbohydrates, flavonoids, phenols and saponins in all plant extracts, suggesting a potential impact on blood glucose control. Notably, presence of phytosterols were observed in all plants except Cyrtochloa luzonica, alkaloisa were found in all plants except Cyrtochloa hirsute and cyrtochloa luzonica, and all species lack glycosides and tannins. The species were ranked based on their concentrations of Total Flavonoid Content (TFC) and Total Phenolic Content (TPC), with Cyrtochloa toppingii having the highest concentration, followed by Cyrtochloa fenixii, Cyrtochloa luzonica, Cyrtochloa major. Among the five species studied, Cyrtochloa toppingii having the highest concentration of flavonoids and phenols showed the highest hypoglycemic activity. Correlation analyses revealed that TFC and TPC directly affect the alpha-amylase inhibition behaviors of plant extracts. In the hypoglycemic properties in terms of their effect on the glucose uptake of yeast cells, moderate and strong positive correlation to TPC and TFC were observed, respectively.
526			_aF
540			_a5
655			_aacademic writing
942			_alcc _cMS _01 _2lcc
999			_c25443 _d25443