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245 0 _a
_aComparative Effects of the Four Leading Brands of Local Cigarettes on the Hemoglobin Concentration and Histopathology of Mice.
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_h6
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246 _a
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_atext
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337 _3
_30
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_aunmediated
_2rdamedia
338 _3
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_avolume
_2rdacarrier
340 _2
_20
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500 _a
_aABSTRACT : The hemoglobin (HGb) concentrations of mice passively exposed to four different brands of local cigarettes labeled A,B,C and D were compared. Further, the extent of hispathological changes on thier lungs, heart, liver and kidney were also examined.After one week post-exposure, alower Hgb concentration was observed in mice exposed to all the four brands of cigarettes as compared to the control (CTRL) mice (28.5g/dL). Mice exposed to brand A gave the lowest Hgb concetration (19.0g/dL0, which implies that among the four cigarette brandss, brand A had the greatest potential to induce anemia. In contrast, Brand C had the Hgb concentration closest to the CTRL, which was 25g/dL. of the different tissues examined, the lungs had the most pronounced changes showing edema, interstitial pneumonitis, congestion, necrosis, hemorrahages. This was followed by the heart tissues , liver and kidneys, however showed minimal histopathological changes relative to the lungs and heart. In terms of the extent of damage made on the tissues, Brand A had the mildest effect while Brand D had the most adverse effect on the vital organs of mice. The findings of this study underscore the role of secondhandsmoke on the development of anemia as well as histopathological damages among exposed individuals.
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540 _c
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542 _g
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546 _a
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583 _5
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590 _a
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600 _b
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630 _x
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648 _2
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_aANEMIA
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_zPASSIVE SMOKING.
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651 _x
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_y20
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655 _0
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700 _i
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_aJulieta Z. Dungca, Catherine Joy Martinez, Frances Karen Hernandez and Anthony Biasura.
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710 _b
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_aGSEAS Graduate Journal. 11 (1) : May 2006. pp. 160-175.
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