Radioprotective potential of leea manillensis syn. Guineensis (abang-abang) leaf extract on gamma-irradiated human blood lymphocytesn in vitro / Charlotte F. Marasigan. 6
By: Charlotte F. Marasigan. 4 0 16 [, ] | [, ] |
Contributor(s): 5 6 [] |
Language: Unknown language code Summary language: Unknown language code Original language: Unknown language code Series: ; March 2017.46Edition: Description: 28 cm. 31 ppContent type: text Media type: unmediated Carrier type: volumeISBN: ISSN: 2Other title: 6 []Uniform titles: | | Subject(s): -- 2 -- 0 -- -- | -- 2 -- 0 -- 6 -- | 2 0 -- | -- -- 20 -- | | -- -- -- -- 20 -- | -- -- -- 20 -- --Genre/Form: -- 2 -- Additional physical formats: DDC classification: | LOC classification: | | 2Other classification:| Item type | Current location | Home library | Collection | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|---|---|
| Book | PLM | PLM Filipiniana Section | Filipiniana-Thesis | T QH450.M37.2017 (Browse shelf) | Available | FT6239 |
Thesis:(B.S. Biology)-Pamantasan ng Lungsod ng Maynila, 2017. 56
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ABSTRACT: The objective of the study was to evaluate the Radioprotective Potential of Leea manillensis syn. guineensis (Abang-abang) extract on gamma irradiated human lymphocytes in vitro using the micronucleus assay. The 100% pure concentration of Leea manillensis syn. guineensis (Abang-abang) extract was diluted into varying concentration of 0.1 mg/ml, 0.2 mg/ml, 0.3 mg/ml, and 0.4 mg/ml which were added to the irradiated blood samples. Based on the experiment, the extract of Leea manillensis syn, guineensis (Abang-abang) reduced the number of the micronuclei in the 1000 binucleated cells. Hoewever only 0.4 mg/ml of Leea manillensis syn. guineenis (Abang-abang) exhibited the greatest radioprotective activity in terms of the reduced micronucleus formation. One-way analysis of variance (ANOVA) was utilized to determine and evaluate if there is a significant difference between the experimental group. It demonstrated that the Leea manillensis syn. guineesis (Abang-abang) extract reduced the number of micronuclei and the highest plant concentration which was 0.4 mg/ml yielded the least number of micronuclei which was 0.4 mg/ml yielded the least number of micronuclei which scored a mean of 33. Furthermore, it was observed and evident that the 0.4 mg/ml plant concentration had no significant difference (p<0.05) from the positive control, oregano extract.
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